A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses

• Status: Completed
• Trial end date: 2019-07-25
• Target enrollment: 0
• Participant gender: All

Summary

This project will further develop and test the Tailored Telephone Intervention delivered by Peers to Prevent Recurring Opioid Overdoses (TTIP-PRO), a promising, low-cost, intervention to facilitate entry into medication assisted treatment (MAT) for individuals experiencing a non-fatal opioid overdoses (OOD). A prior small-scale pilot/feasibility study of TTIP-PRO (NCT02282306) found that the participating patients and the Peer Interventionists were satisfied with their participation, the intervention was acceptable, and the system for generating patient-tailored intervention information performed well. The overall goal of the present study is to conduct a pilot randomized controlled trial of TTIP-PRO versus a control group. It is hypothesized that patients in the TTIP-PRO group will have more favorable drug-abuse-related outcomes than patients in the control group.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Cincinnati
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Analgesics, Opioid; Naloxone

Criteria

Inclusion Criteria:

• Report having been treated for an OOD within the past 6 months

• Age 18 years or older;

• Scores "high risk" for heroin and/or non-medical use of prescription opioids on the National Institute on Drug Abuse modified Alcohol, Smoking and Substance Involvement Screening Test (NIDA-modified ASSIST) (i.e., ≥ 27)

• Be able to understand the study, and having understood, provide written informed consent in English

• Access to a phone (for TTIP-PRO intervention and phone follow-up)

• Be willing to have their intervention audio recorded and rated if randomized to TTIP-PRO

• Have an opioid-positive baseline/screening urine drug screen.

Exclusion Criteria:

• In the judgment of the investigator, would not be expected to complete the study protocol (e.g., due to relocation from the clinic area, probable incarceration, etc.)

• Current engagement in addiction treatment

• Residence more than 40 miles from the location of follow-up visits

• Inability to provide sufficient contact information (must provide at least 2 reliable locators)

• Prior participation in the current study.