A Study to Investigate the Phototoxic Potential of Faldaprevir
Status:
Withdrawn
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
To investigate the potential of Faldaprevir to induce skin phototoxicity, immediate or
delayed type, to UV light and visible light in healthy male and female subjects. To
investigate the degree, wavelength dependency, severity, pigmentation and morphology of the
phototoxic effects. The persistence of the phototoxic susceptibility will be explored
following cessation of study medication. Within a sunscreen sub-study, the efficacy of
commercially available high factor sunscreen will also be assessed in terms of its potential
to prevent any phototoxic skin responses seen. The safety and tolerability of Faldaprevir
will also be assessed.