Overview

A Study to Investigate the Pharmacodynamic Effect After Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population

Status:
Completed
Trial end date:
2004-08-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to investigate the pharmacodynamic effect of omeprazole n a Japanese non-erosive reflux disease population
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
AstraZeneca
Collaborator:
Mitsubishi Tanabe Pharma Corporation
Treatments:
Omeprazole
Criteria
Inclusion Criteria:

- Patients who identified their predominant symptom as heartburn and were classifiend as
Grande M or N according to Hoshihara's modofied version of Los Angeles Classification
at esophagogastroduodenoscopy. Written informed consent, ability to comply with study
instructions

Exclusion Criteria:

- Patients with any ongoing gastrointestinal bleeding at the time of
esopgahogastroduodenoscopy, patients with any history of erosive esophagitis or any
other major diseases or concommittant drugs likely to interfere with the evaluation of
this study