A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

• Status: RECRUITING
• Trial end date: 2026-12-01

Summary

The purpose of this study is to learn more about LP-118 (an experimental drug) and its side effects and decide on acceptable doses. The purpose of this study is to determine if LP-118 can be given safely with another medicine called ponatinib, that is FDA-approved for the treatment of acute lymphoblastic leukemia.

• Phase: PHASE1

Details

• Lead Sponsor: University of Chicago
• Treatments: Calcium Dobesilate; Dexamethasone; Methotrexate; ponatinib; Vincristine