This is a single-centre, open-label, non-randomised, two-arm study in 12 healthy male
volunteers. This study is designed to correlate the gastrointestinal transit behaviour of
delayed-release diclofenac potassium tablets with their pharmacokinetic (PK) absorption
profiles.
We will be looking at:
1. The behaviour of the tablets (when, where and how quickly they break up)
2. The gastric emptying time of the tablets (when they leave the stomach)
3. The gastrointestinal transit of the tablets (how long they take to travel through the
gut)
4. Blood levels of the drug (diclofenac)