Overview

A Study to Find a Suitable Dose of Exl-111 for Further Research

Status:
NOT_YET_RECRUITING
Trial end date:
2026-12-07
Target enrollment:
Participant gender:
Summary
This is a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose trial of Exl-111 in healthy participants. The trials consists of 2 parts, as follows: Part A (SAD): Up to 5 dose cohorts, each with 8 participants, randomized into 2 arms: Exl-111 and placebo. Part B (MAD): Up to 3 dose cohorts, each with 10 participants, randomized into 3 arms: Exl-111, placebo, and an active comparator (omalizumab).
Phase:
PHASE1
Details
Lead Sponsor:
Excellergy Inc.
Treatments:
mycophenolic adenine dinucleotide
Omalizumab
Sagittal Abdominal Diameter