Overview

A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

Status:
Unknown status

Trial end date:
2010-04-01

Target enrollment:

Participant gender:

Summary

The primary objectives of this exploratory study are to evaluate the effects of bosentan on hemodynamics (via cardiac catheterization) during exercise in patients with Pulmonary Arterial Hypertension (PAH) who have abnormal hemodynamics during exercise but normal hemodynamics at rest. The authors hypothesize that early treatment may change the course of disease progression by improving hemodynamics during exercise, thus delaying disease progression.

Phase:

Phase 3

Details

Lead Sponsor:

Hamilton Health Sciences Corporation

Collaborator:

Actelion

Treatments:

Bosentan