Overview

A Study to Evaluate the Pharmacokinetics of Margetuximab in Chinese Patients With HER2+ MBC

Status:
Completed
Trial end date:
2021-04-27
Target enrollment:
Participant gender:
Summary
This is an open-label, Single-arm, Phase I clinical study to evaluate the pharmacokinetics, tolerability and safety of margetuximab plus chemotherapy in Chinese patients with advanced HER2+ breast cancer who have received standard anti-HER2 directed therapy in the metastatic setting (mandatory including trastuzumab). The primary endpoint of this study is PK parameters of margetuximab.
Phase:
Phase 1
Details
Lead Sponsor:
Zai Lab (Shanghai) Co., Ltd.
Treatments:
Antibodies, Monoclonal
Margetuximab