A Study to Evaluate the Effect of Single Doses of Drug A (Lamotrigine) and Drug B (Vofopitant) Alone and in Combination on Resting Motor Threshold in Healthy Subjects

• Status: Terminated
• Trial end date: 2010-06-10

Summary

The purpose of this study is to investigate the effect of drug A on its own and when it is given in combination with drug B on markers of brain activity. The study will

1. Assess the effects of drug A and drug B on muscle movement after brain stimulation;

2. Examine how the body handles (absorbs, distributes, breaks down and gets rid of) drug A and drug B when given in combination;

3. Examine the safety of drug A and drug B when given together.

• Phase: Phase 1

Details

• Lead Sponsor: GlaxoSmithKline
• Treatments: Anticonvulsants; Lamotrigine; Vofopitant