A Study to Evaluate the Effect of LCZ696 on Aortic Stiffness in Subjects With Hypertension
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
This was the first evaluation of the effects of LCZ696 on local and regional measures of
aortic stiffness in subjects with mild to moderate hypertension and widened pulse pressure.
The results of this exploratory study will help to understand the mechanism of action of
LCZ696 and used to inform the design of future clinical studies with LCZ696 in subjects with
cardiovascular diseases.
Phase:
Phase 2
Details
Lead Sponsor:
Novartis Pharmaceuticals
Treatments:
Amlodipine LCZ 696 Olmesartan Olmesartan Medoxomil Sacubitril and valsartan sodium hydrate drug combination Valsartan