Overview

A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Status:
Completed
Trial end date:
2021-06-02
Target enrollment:
Participant gender:
Summary
It is a phase 1, open-label, single-center, three-part study to assess the safety, tolerability, and pharmacokinetics of multiple doses of CC-99677 administered alone or in combination with either methotrexate and sulfasalazine; itraconazole, rifampin, midazolam, or a cocktail of digoxin, metformin, and rosuvastatin in healthy subjects
Phase:
Phase 1
Details
Lead Sponsor:
Celgene
Treatments:
Digoxin
Hydroxyitraconazole
Itraconazole
Metformin
Methotrexate
Midazolam
Rifampin
Rosuvastatin Calcium
Sulfasalazine