Overview

A Study to Evaluate Neoadjuvant Sonidegib Followed by Surgery or Imiquimod in the Management of Basal Cell Carcinoma

Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
In this study, patients with BCC will be given neoadjuvant treatment with a drug called sonidegib. Sonidegib is a daily tablet usually given for BCC that cannot be removed by surgery or that has spread through the body. The study aims to see if sonidegib given for 12 weeks will reduce the size of tumours so surgery results in less scarring or may be avoided, with only short term topical treatment required to treat remaining tumour.
Phase:
Phase 2
Details
Lead Sponsor:
Melanoma Institute Australia
Treatments:
Imiquimod