A Study to Evaluate Efficacy of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis
Status:
Terminated
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
This study will compare the efficacy of CellCept [0.5-2 grams per day (g/day) orally (p.o.)]
and cyclophosphamide [0.5-1 grams per square meter (g/m2) quarterly] as maintenance treatment
for patients with lupus nephritis. All patients will receive induction treatment with
cyclophosphamide (0.5-1g/m2 monthly) for 6 months, and will then be randomized to the
maintenance phase of the study for a further 6 months, followed by 6 months of treatment-free
follow-up. The anticipated time on study treatment is 12 months.