A Study to Evaluate Aprepitant for the Prevention of Post-Operative Nausea and Vomiting in Children (MK-0869-219)
Status:
Completed
Trial end date:
2016-09-26
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability
of aprepitant for the prevention of post-operative nausea and vomiting (PONV) in pediatric
participants.
Post-operative aprepitant plasma concentrations will be evaluated with a non-compartmental
analysis (NCA) at each dose and for each age cohort. Full PK profiles analyzed using
population PK modeling and simulation will be described in a separate report.