Overview

A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects

Status:
Completed

Trial end date:
2019-01-19

Target enrollment:

Participant gender:

Summary

This is a Phase 1, randomized, 2 way crossover, open-label study of the effect of multiple-dose PF 04965842 on single-dose OC PK in healthy female subjects. Subjects will be randomized to 1 of 2 treatment sequences. A total of 16 healthy female subjects (8 in each treatment sequence) will be enrolled in the study. Each treatment sequence will consist of 2 periods.

Phase:

Phase 1

Details

Lead Sponsor:

Pfizer

Treatments:

Abrocitinib
Contraceptive Agents
Contraceptives, Oral
Estradiol
Ethinyl Estradiol
Levonorgestrel