A Study to Compare Two Different Anti-HIV Drug Regimens
Status:
Completed
Trial end date:
2001-06-01
Target enrollment:
Participant gender:
Summary
This study compares 2 different anti-HIV drug regimens to determine which is the most
effective in lowering the amount of HIV in the blood. The anti-HIV drugs used in this study
are 2 protease inhibitors (nelfinavir and ritonavir), 2 nucleoside reverse transcriptase
inhibitors (stavudine and didanosine), and 1 nonnucleoside reverse transcriptase inhibitor
(nevirapine).
These drug combinations have been previously studied in adults, but there is limited
information on how well they work in HIV-infected children. It is important to develop drug
combinations which are effective at suppressing the HIV virus in children.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Treatments:
Didanosine HIV Protease Inhibitors Nelfinavir Nevirapine Protease Inhibitors Ritonavir Stavudine