A Study to Compare Oxybutynin to a Placebo in Women and the Effect on Plantar Hyperhidrosis

• Status: Completed
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

A study in which the experimental treatment procedure is compared to a standard (control) treatment, The use of oxybutynin in the late postoperative thoracic sympathectomy for women:

1. To Evaluate the effect of oxybutynin on plantar hyperhidrosis.

2. To evaluate the effect of oxybutynin in compensatory hyperhidrosis.

3. To compare the results of questionnaires on quality of life and specific for hyperhidrosis to the results of TEWL.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal University of São Paulo
• Treatments: Cholinergic Antagonists; Mandelic Acids; Oxybutynin

Criteria

Inclusion Criteria:

• women with persistent plantar hyperhidrosis with limitation to their usual activities.

Exclusion Criteria:

• pregnancy,

• breastfeeding,

• glaucoma,

• use of tricyclic medications,

• prior use of anticholinergic

• side effects exacerbated, such as diarrhea, gastritis, constipation or dry mouth.