A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation
Status:
Completed
Trial end date:
2006-01-01
Target enrollment:
Participant gender:
Summary
Anti-HIV drug therapy works best when the drugs are taken exactly as prescribed by a doctor.
Because anti-HIV therapy often involves multiple drugs, some people have difficulty taking
them all correctly. The easier it is to take anti-HIV drugs, the more likely people will take
them as prescribed and get the best results. This study will see if people are more
successful in taking anti-HIV drugs once a day or twice a day. It also will determine if
having a health care professional oversee each weekday dose helps people control their HIV
infection. The study will compare taking a three-drug combination twice a day versus taking a
three-drug combination just once a day. The study will also compare patients taking the drugs
on their own to patients taking the drugs in the presence of a clinical worker. Viral load
(amount of HIV in the blood) and drug side effects will be measured.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)