A Study to Assess Relative Bioavailability and Food Effect of New Formulations of GSK2248761
Status:
Completed
Trial end date:
2010-03-11
Target enrollment:
Participant gender:
Summary
This is a single-center, randomized, two part, open-label, crossover study in healthy adult
subjects to assess the effect of up to three formulations on the relative bioavailability of
GSK2248761 100mg administered with and without food. Part A will evaluate two new
formulations compared to the current formulation. Part B will evaluate one additional
formulation if the bioavailability of the two formulations in Part A do not meet
pre-specified criteria. Safety evaluations and serial PK samples will be collected during
each treatment period. A follow-up visit will occur 7-10 days after the last dose of study
drug.