Overview

A Study of the IDH1 Inhibitor AG-120 in Combination With the Checkpoint Blockade Inhibitor, Nivolumab, for Patients With IDH1 Mutated Relapsed/Refractory AML and High Risk MDS

Status:
Withdrawn

Trial end date:
2023-09-01

Target enrollment:

Participant gender:

Summary

In this trial the investigators aim to evaluate safety and efficacy of combination Ivosidenib (AG-120) and nivolumab in the context of adult patients with Isocitrate dehydrogenase-1 (IDH1) mutated acute myeloid leukemias (AML) or Myelodysplastic syndromes (MDS).

Phase:

Phase 2

Details

Lead Sponsor:

Yale University

Treatments:

Ivosidenib
Nivolumab