A Study of the Effects of Risperidone and Olanzapine on Blood Glucose (Sugar) in Patients With Schizophrenia or Schizoaffective Disorder

• Status: Completed
• Trial end date: 2003-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess and compare how risperidone and olanzapine, two antipsychotic medications, affect the regulation of glucose (sugar) in the body.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Janssen, LP
• Treatments: Olanzapine; Risperidone

Criteria

Inclusion Criteria:

• Diagnosis of schizophrenia or related disorder

• stable with respect to disease symptoms and other medical conditions

• would benefit from this type of antipsychotic drug

• if female, using birth control.

Exclusion Criteria:

• Patients who are delirious, bipolar, severely mentally retarded, or suicidal

• psychiatric diagnosis of disease unrelated to schizophrenia

• presence of stroke, brain tumor, Parkinson's Disease, or diseases that affect blood glucose control

• history of diabetes

• long or recent history of taking risperidone, olanzapine, quetiapine, clozapine, or investigational drugs

• recent history of unstable thyroid function

• if female, not using birth control

• abusing drugs or alcohol.