A Study of the Effects of Ketoconazole Taken Orally Has on the PK Profiles of a Dose of GSK189075 in Healthy Volunteers
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to evaluate the effect of several daily doses of
ketoconazole (a medication used to treat fungal infections like athlete's foot) on a single
dose of GSK189075 (an experimental diabetes drug), and also to evaluate the safety and
tolerability of GSK189075 in healthy volunteers. The study will see whether ketoconazole
causes GSK189075 to stay in your bloodstream for a longer period of time. It will also
examine whether GSK189075 causes any changes in the amount of glucose you have in your urine.