A Study of the Effectiveness of Anti-Arrhythmic Medications After Atrial Fibrillation Ablation

• Status: Completed
• Trial end date: 2008-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the overall effectiveness of anti-arrhythmic medicines (to control heart rhythm) prescribed after an ablation procedure for atrial fibrillation.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Pennsylvania
• Treatments: Anti-Arrhythmia Agents; Dofetilide; Flecainide; Propafenone; Sotalol

Criteria

Inclusion Criteria:

• Adult patients meeting ACC/AHA criteria for paroxysmal atrial fibrillation (episodes typically last no more than 7 days and are self-terminating)

• Eligible for pulmonary vein isolation

• Able to tolerate antiarrhythmic medication

Exclusion Criteria:

• Age <18

• Persistent or permanent atrial fibrillation (episodes last >7 days and require cardioversion)

• Antiarrhythmic treatment for indication other than atrial fibrillation

• Contraindication or intolerance to all antiarrhythmic medications

• Primary physician unwilling to withhold antiarrhythmic drugs for duration of the study

• Failure to obtain informed consent