A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor
Status:
Completed
Trial end date:
2018-03-28
Target enrollment:
Participant gender:
Summary
The study is an experimental observational study in ten healthy volunteers. Based on an in
vitro study, it is hypothesize that a low dose epinephrine infusion will improve platelet
function in healthy volunteers who have received ticagrelor. Volunteers fulfilling all of the
inclusion and none of the exclusion criteria will be included. Enrollment will be continued
until the required sample size is achieved (10 subjects).
Once informed consent is obtained, screening data will be collected to determine each
subject's eligibility for study participation. The total expected duration of subject
participation is 18 days, from screening visit to end of follow-up. The active participation
is 8h (study procedure 4 hours, observation period 4 hours).
Phase:
Phase 1
Details
Lead Sponsor:
Vastra Gotaland Region
Collaborators:
Gothia Forum Gothia Forum - Center for Clinical Trial Uppsala University