A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia
Status:
Completed
Trial end date:
2021-04-09
Target enrollment:
Participant gender:
Summary
The goal of this study is to see if the study therapy can decrease the chemotherapy-related
side effects while maximizing the effectiveness of disease control. The physicians will also
be studying the effect of removing T-cells from the donor"s stem cells before transplant.
T-cells are a type of white blood cell that may help cause a serious side effect of
transplant called Graft versus Host Disease (GVHD). The way it removes the T-cells from the
donor stem cells is actually by selecting only the stem cells (called CD34 cells) by using a
device called CliniMACS. This process is called CD34 selection. The CliniMACS® device is
currently under the supervision of the FDA .