Overview

A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer

Status:
Recruiting
Trial end date:
2025-10-31
Target enrollment:
Participant gender:
Summary
This trial studies how well the drug tucatinib works when given with trastuzumab deruxtecan. It will also look at what side effects happen when these drugs are given together. A side effect is anything a drug does besides treating cancer. Participants in this trial have HER2-positive (HER2+) breast cancer that has either spread to other parts of the body (metastatic) or cannot be removed completely with surgery (unresectable). All participants will get both tucatinib and trastuzumab deruxtecan.
Phase:
Phase 2
Details
Lead Sponsor:
Seagen Inc.
Seattle Genetics, Inc.
Treatments:
Trastuzumab
Tucatinib