Overview

A Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer

Status:
Completed
Trial end date:
2020-09-03
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the maximal tolerated dose (MTD) or recommended dose (RD) and to assess the safety and tolerability of tucatinib (ONT-380) combined with ado-trastuzumab emtansine (T-DM1) in patients with HER2+ breast cancer.
Phase:
Phase 1
Details
Lead Sponsor:
Cascadian Therapeutics Inc.
Seagen Inc.
Treatments:
Ado-trastuzumab emtansine
Maytansine
Trastuzumab
Tucatinib