Overview

A Study of Targeted Agents With Atezolizumab for Patients With Recurrent or Persistent Endometrial Cancer

Status:
Recruiting
Trial end date:
2026-10-01
Target enrollment:
Participant gender:
Summary
This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents plus cancer immune checkpoint therapy with atezolizumab for patients with recurrent and/or persistent endometrial cancer. The main protocol provides a platform for genomic screening with homogeneous basic eligibility criteria in order to direct study subjects into biomarker-matched study cohorts consisting of testing targeted agents with atezolizumab.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Alliance Foundation Trials, LLC.
Collaborators:
Foundation Medicine
Genentech, Inc.
Pfizer
Treatments:
Atezolizumab
Bevacizumab
Talazoparib