This trial will study SGN-CD228A to find out whether it is an effective treatment for
different kinds of cancer. It will also look at what side effects (unwanted effects) may
occur. The study will have two parts. Part 1 of the study will find out how much SGN-CD228A
should be given for treatment and how often. Part 2 of the study will use the dose found in
Part 1 and look at how safe and effective the treatment is.