Overview

A Study of Ramucirumab (IMC-1121B) and Paclitaxel in Participants With Solid Tumors

Status:
Completed
Trial end date:
2021-02-22
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate whether there are no clinically significant pharmacokinetic effects of concomitant ramucirumab (IMC-1121B) on paclitaxel by investigating the pharmacokinetics (PK) of each in participants with advanced malignant solid tumors. Part A of this study will investigate the potential of concomitant ramucirumab (IMC-1121B) to affect the pharmacokinetics of paclitaxel. Part B of this study will investigate the pharmacokinetics of ramucirumab (IMC-1121B) as monotherapy.
Phase:
Phase 2
Details
Lead Sponsor:
Eli Lilly and Company
Treatments:
Albumin-Bound Paclitaxel
Antibodies, Monoclonal
Paclitaxel
Ramucirumab