Overview

A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma

Status:
Recruiting
Trial end date:
2023-04-01
Target enrollment:
Participant gender:
Summary
This is a non-randomized, open-label, multi-site phase II therapeutic trial of pembrolizumab and bavituximab in patients with locally advanced HCC. Locally advanced or metastatic HCC is defined as disease that is not amenable to surgical and/or locoregional therapies. Subjects must not have received prior systemic therapy for advanced HCC in keeping with the first-line setting of this study.
Phase:
Phase 2
Details
Lead Sponsor:
Muhammad Beg
University of Texas Southwestern Medical Center
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Antibodies, Monoclonal
Bavituximab
Pembrolizumab