Overview

A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia

Status:
Completed
Trial end date:
2017-07-31
Target enrollment:
Participant gender:
Summary
This Phase 3 study assesses two drug regimens as the initial treatment of patients who are at least 70 years of age and have newly diagnosed acute myeloid leukemia (AML) for whom the doctor does not recommend the use of standard intensive treatment or the patient has decided not to receive standard intensive treatment after being fully informed about its benefits and risks by his/her doctor. The two drug regimens are sapacitabine administered in alternating cycles with decitabine or decitabine alone. The purpose of the study is to learn which drug regimen is more likely to keep AML in check as long as possible.
Phase:
Phase 3
Details
Lead Sponsor:
Cyclacel Pharmaceuticals, Inc.
Treatments:
Azacitidine
Decitabine
Sapacitabine