Overview

A Study of Nivolumab +/- Nab-paclitaxel in Non-small Cell Lung Cancer

Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The optimal prioritization of second-line chemotherapy and immune therapy based on demographic or biomarker data is an area of ongoing investigation. The hypothesis of this study is that there may be an additive or synergistic antitumor effect of combined chemotherapy and nivolumab in the second-line treatment of NSCLC as an important concept to test in a clinical trial. Previously treated NSCLC remains a setting of unmet clinical need despite recent clinical research progress. Early progression for a subset of NSCLC patients receiving nivolumab is a specific area of clinical need.
Phase:
Phase 2
Details
Lead Sponsor:
Alliance Foundation Trials, LLC.
Collaborators:
Bristol-Myers Squibb
Celgene Corporation
Treatments:
Albumin-Bound Paclitaxel
Antibodies, Monoclonal
Nivolumab
Paclitaxel