A Study of N-acetylcysteine in Patients With COVID-19 Infection
Status:
Active, not recruiting
Trial end date:
2023-05-01
Target enrollment:
Participant gender:
Summary
The study researchers think that a medication called N-acetylcysteine can help fight the
COVID-19 virus by boosting a type of cell in your immune system that attacks infections. By
helping your immune system fight the virus, the researchers think that the infection will get
better, which could allow the patient to be moved out of the critical care unit or go off a
ventilator, or prevent them from moving into a critical care unit or going on a ventilator.
The US Food and Drug Administration (FDA) has approved N-acetylcysteine to treat the liver
side effects resulting from an overdose of the anti-inflammatory medication Tylenol®
(acetaminophen). N-acetylcysteine is also used to loosen the thick mucus in the lungs of
people with cystic fibrosis or chronic obstructive pulmonary disease (COPD). This study is
the first to test N-acetylcysteine in people with severe COVID-19 infections.