Overview

A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome

Status:
RECRUITING
Trial end date:
2029-03-06
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to determine if momelotinib is safe and effective for people with low-risk myelodysplastic syndromes (LR-MDS). The trial will also examine how the body processes the drug. The study is comprised of two parts: Part 1: Participants will receive different doses of momelotinib to find the best dose by evaluating effectiveness in improving red blood cell transfusion requirements and safety. Part 2: Participants will receive dose selected from Part 1 to assess its impact on improving red blood cell transfusion requirements and safety in LR-MDS.
Phase:
PHASE2
Details
Lead Sponsor:
GlaxoSmithKline
Treatments:
N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide