A Study of Medication With or Without Psychotherapy for Complicated Grief

• Status: Completed
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The major goal of this 4-site, double blind, placebo-controlled intervention trial is to assess the efficacy of medication (Citalopram) alone or with psychotherapy (Complicated Grief Therapy) to treat the symptoms of complicated grief.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: New York State Psychiatric Institute
• Collaborators: American Foundation for Suicide Prevention; National Institute of Mental Health (NIMH)
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Diagnosed with Complicated Grief and this is the patient's most important (primary) problem

• Ability to give informed consent

• Fluent in English

• Willingness to have sessions audiotaped

• Willingness to undergo random assignment

Exclusion Criteria:

• Diagnosis of one or more of the following disorders: Schizophrenia or other psychotic disorder, current (past 6 months) substance abuse, Bipolar Disorder, current manic episode, Dementia

• Pregnant or lactating women and women of childbearing potential not using medically accepted forms of contraception

• Acute, unstable or severe medical illness such as (but not limited to) stroke, epilepsy, or other neurodegenerative disorders, metastatic or active cancer, hepatic disease, or primary renal disease requiring dialysis

• Prior intolerance of citalopram

• Pending or active disability claim or lawsuit related to the death