A Study of MK0594 in Patients With Alcohol Dependence (0594-020)

• Status: Terminated
• Trial end date: 2010-03-11
• Target enrollment: 0
• Participant gender: All

Summary

A study in patients with alcohol dependence to see if MK0594 is safe and effective in maintaining absence of heavy drinking over a 12-week treatment period.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.; Vyne Therapeutics Inc.

Criteria

Inclusion Criteria:

• Patient has Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision diagnosis of alcohol dependence and alcohol addiction

• Patient has two heavy drinking days in the last 30 days

• Patient has 3 days of abstinence from alcohol right before taking study medication

• Patient has lived in the same residence for the last 2 months

Exclusion Criteria:

• If female, patient is pregnant or breastfeeding

• Patient anticipated inpatient alcohol treatment

• Patient has a history of suicide attempt in the last year

• Patient has schizophrenia or bipolar disorder

• Patient has a history of multiple or serious allergies

• Patient has participated in a clinical trial in the last 30 days