Overview

A Study of Ibrutinib With Rituximab in Relapsed/Refractory Mantle Cell Lymphoma

Status:
Not yet recruiting
Trial end date:
2033-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the recommended dosage of ibrutinib when administered in combination with rituximab in participants with relapsed or refractory (r/r) mantle cell lymphoma (MCL) (Phase 2); and to compare the progression-free survival (PFS) of ibrutinib plus rituximab versus physician's choice of lenalidomide plus rituximab or bortezomib plus rituximab (Phase 3).
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Janssen Research & Development, LLC
Collaborator:
Pharmacyclics LLC.
Treatments:
Bortezomib
Lenalidomide
Rituximab