A Study of Epidural Bupivacain-soaked Absorbable Gelatin Sponge on Post-operative Pain in Lumbar Laminectomy
Status:
Withdrawn
Trial end date:
2015-02-12
Target enrollment:
Participant gender:
Summary
The effective relief of pain is of paramount importance to anyone treating patients
undergoing surgery. Post-operative pain increases the possibility of post-surgical
complications, raises the cost of medical care, and most importantly, interferes with
recovery and return to normal activities of daily living. Therefore pain control is essential
in the management of patients undergoing spinal surgery.Parenteral administration of
narcotics has been the mainstay for postoperative pain relief in patients undergoing
laminectomy and discectomy. Epidural and intrathecal opioids are also effective means of pain
control in several major surgical interventions including spinal surgery. However, some of
the side effects have limited their widespread use (eg, late-onset respiratory depression).
Therefore, alternative measures of pain control including infiltration of paraspinal
musculature with local anesthetics have been investigated with conflicting results. In
situations such as laminectomies, where the epidural space is exposed as part of the surgical
procedure, the application of absorbable gelatin sponge soaked in local anesthetics appears
to be an alternative for providing postoperative analgesia. By investigating the probable
analgesic effects of this method the investigators may relieve post laminectomy pain with
minimal side effects and also costs.