A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
To compare the effects of megestrol acetate and placebo on body weight, anorexia, cachexia,
calorie intake, and nutritional parameters of patients with a confirmed diagnosis of AIDS. To
characterize dose response in relation to weight gain. To determine whether megestrol acetate
relative to placebo improves the perception of well-being among AIDS patients with cachexia.
To evaluate megestrol acetate's effect on immune function via skin test reactivity, T4/T8
ratio, and total lymphocytes.