Overview

A Study of Dasatinib, Cetuximab and Radiation With or Without Cisplatin in HNSCC

Status:
Terminated
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Primary Objective for Phase I 1. To determine the maximally tolerated dose (MTD) of daily Oral dasatinib in combination with cetuximab/RT in Cohort A. 2. To determine the MTD of daily oral dasatinib in combination with cisplatin/cetuximab/RT in Cohort B
Phase:
Phase 1
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborator:
Bristol-Myers Squibb
Treatments:
Cetuximab
Cisplatin
Dasatinib