Overview

A Study of Belinostat + Carboplatin or Paclitaxel or Both in Patients With Ovarian Cancer in Need of Relapse Treatment

Status:
Completed
Trial end date:
2009-02-01
Target enrollment:
Participant gender:
Summary
The study seeks to assess the safety, pharmacodynamics, pharmacokinetics and efficacy of belinostat (PXD101) administered in combination with carboplatin or paclitaxel or both in patients with solid tumours followed by maximum tolerated dose (MTD) expansion (phase II) in ovarian and bladder cancer patients The clinical trial is now in the MTD (phase II) portion of the study enrolling bladder cancer patients. Enrollment of ovarian patients is complete.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Onxeo
Treatments:
Albumin-Bound Paclitaxel
Belinostat
Carboplatin
Paclitaxel