Overview
A Study of BMS-986195 in Healthy Male Subjects
Status:
Completed
Completed
Trial end date:
2017-10-05
2017-10-05
Target enrollment:
0
0
Participant gender:
Male
Male
Summary
The purpose of this study is to investigate the effects BMS-986195 in healthy male subjects.Phase:
Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Bristol-Myers SquibbTreatments:
Branebrutinib
Criteria
For more information regarding Bristol-Myers Squibb Clinical Trial participation, pleasevisit www.BMSStudyConnect.com
Inclusion Criteria:
- Male subjects, if not surgically sterilized, must agree to use adequate contraception
- Body mass index (BMI) of 18.0 to 32.0 kg/m2, inclusive (BMI = weight [kg]/[height
(m)]2), and total body weight >50 kg
- All prescribed medication, including live vaccinations, must have been stopped at
least 30 days prior to admission to the clinical research center
- All over-the-counter (OTC ) medication, vitamin preparations and other food
supplements, or herbal medications (eg, St. John's Wort) must have been stopped at
least 14 days prior to admission to the clinical research center
- Ability and willingness to abstain from alcohol, methylxanthine-containing beverages
or food (coffee, tea, cola, chocolate, energy drinks), and grapefruit (juice) from 3
days prior to admission to the clinical research center
- Good physical and mental health on the basis of medical history, physical examination,
clinical laboratory, ECG and vital signs, as judged by the Principal Investigator
Exclusion Criteria:
- Previous participation in the current study
- Known previous exposure to BMS-986195
- Employee of PRA or the Sponsor
- History of relevant drug and/or food allergies, including allergy to immunologic or
related compounds or allergy to seafood or marine products
- Using tobacco products within 60 days prior to drug administration
- Positive screen for hepatitis B surface antigen (HBsAg), anti-hepatitis C virus (HCV)
antibodies or anti-human immunodeficiency virus (HIV) 1 and 2 antibodies
Other protocol defined inclusion/exclusion criteria could apply