Overview A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) Status: Recruiting Trial end date: 2028-06-01 Target enrollment: Participant gender: Summary The purpose of this study is to evaluate the effectiveness and mechanism of action of Losartan in the treatment of coarctation of aorta. Phase: Phase 3 Details Lead Sponsor: Mayo ClinicCollaborator: National Heart, Lung, and Blood Institute (NHLBI)Treatments: AmlodipineLosartan