Overview

A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood

Status:
COMPLETED
Trial end date:
2024-12-18
Target enrollment:
Participant gender:
Summary
For Part 1 of the trial, the main objective is to assess the effect of a single dose of zongertinib on the pharmacokinetics of a single dose of dabigatran-etexilate. For Part 2 of the trial, the main objective is to assess the effect of zongertinib at steady-state on the pharmacokinetics of a single dose of rosuvastatin, metformin and furosemide (administered as a cocktail).
Phase:
PHASE1
Details
Lead Sponsor:
Boehringer Ingelheim
Treatments:
Dabigatran
Furosemide
Metformin
Rosuvastatin Calcium