A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects
Status:
Completed
Trial end date:
2020-01-03
Target enrollment:
Participant gender:
Summary
The purposes of this study are to:
1. Learn about the safety of CK-3773274 after a single dose and multiple doses in healthy
subjects.
2. Learn how healthy subjects tolerate CK-3773274 after a single dose and multiple doses.
3. Find out how much CK-3773274 is in the blood after a single dose and multiple doses.
4. Determine the effect of doses of CK-3773274 on the pumping function of the heart.
5. Evaluate the effect of cytochrome genetic variants on how the body metabolizes
CK-3773274.
6. Evaluate the effect of a meal on how much CK-3773274 is in the blood in healthy adult
subjects.
7. Evaluate whether the amount of CK-3773274 in the blood is the similar for both the
tablet and granules in capsule forms of the drug.