A Single Dose, Tolerance and Pharmacokinetic Study in Obese or Overweight Type 2 Diabetic Volunteers
Status:
Completed
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the safety and tolerance of a single intravenous
(through a vein) dose of trodusquemine (MSI-1436) in obese, type 2 diabetics.
Different amounts of trodusquemine (MSI-1436) will be given to each volunteer group
throughout the study.
Another purpose is to evaluate the pharmacokinetics (PK - the study of the way the drug
enters and leaves the blood and tissues over time) of trodusquemine (MSI-1436).
Finally, this study will also determine whether trodusquemine (MSI-1436) has any effect on
appetite, mood or behavior, and selective biomarkers (substances in your blood that may
change in response to the study drug).