A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
Pediatric cerebral malaria (CM) affects more than 3 million children each year killing ~20%
and leaving one third of survivors with long term neurologic and psychiatric sequelae.
Seizures occur commonly with CM and are associated with an increased risk of death and
neuropsychiatric disabilities. In this Malawi-based, safety and feasibility study of enteral
levetiracetam in pediatric CM, the investigators will lay the groundwork for future efficacy
studies aimed at improving seizure control and ultimately decreasing the neurologic morbidity
of pediatric CM.
Phase:
Phase 2
Details
Lead Sponsor:
University of Rochester
Collaborator:
National Institute of Neurological Disorders and Stroke (NINDS)