A Safety and Efficacy of CCRT With Paclitaxel as Adjuvant Therapy to Post-Operative Advanced Endometrial Cancer Patients

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether post-operative concurrent chemoradiation with paclitaxel is effective and safe in the treatment of high risk postoperative endometrial cancer patients.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Korean Gynecologic Oncology Group
• Treatments: Albumin-Bound Paclitaxel; Paclitaxel

Criteria

Inclusion Criteria:

• Patients undertaken total hysterectomy, bilateral salpingoophorectomy, washing cytology, pelvic and paraaortic lymph node dissection

• Patients must have the diagnosis of endometrioid type adenocarcinoma with stage III, IV.

• Patients must have a GOG performance of 0, 1, or 2.

• Patients must have expected life span over 6 months.

Exclusion Criteria:

• Patients with peripheral neurotoxicity over grade 2 in CTC criteria.

• Patients with history of chemotherapy or radiation treatment.

• patients with history of arrhythmia,congestive heart failure.

• Patients with intractable infection.