A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP
Status:
Recruiting
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess the safety and efficacy of adjuvanted R21 alone and
in combination with viral-vectored vaccine regimen (constituting adjuvanted R21 + ChAd63 and
MVA encoding ME-TRAP) against malaria sporozoite challenge in healthy malaria-naive
volunteers.
Healthy adult volunteers will be recruited in London, Oxford and Southampton, England.
All vaccinations will be administered intramuscularly. Each volunteer will receive either
three or five vaccinations in total, depending on the group.